L-GLUTAMINE FOR RECOVERY, STRENGTH, STRESS AND INJURY
Studies have shown that L-Glutamine supplementation can minimize breakdown of muscle and improve protein metabolism. Glutamine ingestion has been shown to quicken the recovery rate of peak force production and decrease muscle soreness ratings over a 72-hr recovery period. L-glutamine resulted in lower muscle soreness after exercise. L-glutamine supplementation in one published study resulted in faster recovery of peak torque and diminished muscle soreness following eccentric exercise. The effect of L-glutamine on muscle force recovery may be greater in men than women.
L-Glutamine is the most abundant amino acid in the bloodstream. It fulfills a number of biochemical needs. It operates as a nitrogen shuttle, taking up excess ammonia and forming urea. It can contribute to the production of other amino acids, glucose, nucleotides, protein, and glutathione.
It is classified as a charge-neutral, polar amino acid. It is non-essential and conditionally essential in humans, meaning the body can usually synthesize sufficient amounts of it, but in some instances of stress, the body's demand for glutamine increases, and glutamine must be obtained from the diet.
Glutamine, traditionally considered a nonessential amino acid, now is considered "conditionally essential" after critical illness, stress, and injury. States of illness or injury can lead to a significant decrease in plasma levels of glutamine, and when this decrease is severe, it has been correlated with increased mortality. Laboratory data have demonstrated numerous benefits of glutamine in experimental models of critical illness, cancer, and cardiac injury.
High-dose or parenteral (> 0.25 to 0.30 g/kg/day IV or >or=30 g/day enterally) glutamine appears to demonstrate the greatest potential for benefit in hospitalized patients. No evidence of harm has been observed in studies conducted to date.
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*These statements have not been evaluated by the FDA. These products are not intended to diagnose, cure, treat, or prevent any disease.